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Die Rezeptur‑Helpdesk enthält mehr als 1500 Fragen und Antworten zu verschiedenen galenischen Themen, alle bereitgestellt von Prof. R. Kinget.
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Regarding the mebeverine syrup compounded as an alternative to Duspatalin syrup, which uses disodium pamoate monohydrate, is there an alternative available since this raw material is apparently no longer obtainable?
How can a 10% N-acetylcysteine and 5% urea cream be prepared for a patient with ichthyosis using 2.5 g sodium hydroxide, 25 g Neo-PCL Base, 5 g glycerin, 1.5 ml rosemary oil, and sterile water up to 100 ml, following a specific heating and mixing method to achieve a pH between 4.5 and 5.0, and is this preparation sensitive to oxidation or should the sodium hydroxide be omitted due to pH concerns?
What is the recommended procedure for a prescription of Isobetadine gel with powdered sugar, noting that this prescription has already been received?
How is this dental gel with triamcinolone acetonide prepared, given the formula of 60 mg triamcinolone acetonide, 45 g glycerin, 5 g starch, 100 mg vanillin, and water up to 60 g to create a gum paste that must be stored in the refrigerator?
What is the expiration date for a reimbursed magistral preparation of capsules whose formula is not in the TMF, given that the TMF states most preparations are limited to 2 months, yet an article from the Farmaceutisch Tijdschrift voor België (2010, N. Duquet) suggests 6 months for non-validated formulas and 1 year for FN or FMS formulas unless otherwise specified?
Why does a boric acid ovule prepared with agar-agar instead of the prescribed gelatin appear to dissolve very slowly, specifically when using a formula of 600 mg boric acid, 0.166 g agar, 2.5 g water, and 2.16 g glycerol, given that a patient reported the ovule had still not dissolved by the morning after evening application?
How can a suspension be prepared containing 6 g of precipitated sulfur, 15 g each of zinc oxide and talc, 0.5% menthol, 15 g of glycerin, and equal parts alcohol and water up to 100 ml?
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