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Die Rezeptur‑Helpdesk enthält mehr als 1500 Fragen und Antworten zu verschiedenen galenischen Themen, alle bereitgestellt von Prof. R. Kinget.
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How should a prescription for a penetrating ointment containing 10% ketamine, 0.3% clonidine, and 5% diclofenac be handled given that ketamine HCl bulk powder costs €90 for 10g, and can Ketalar ampoules (50mg/ml) be used as a cheaper alternative despite the large volume required to reach a 10% concentration, or is the PLO gel mentioned by KU Leuven available as a finished product in Belgium, and if so, who is the supplier, considering Pentravan cream costs €32.46?
How can L-arginine be properly processed into a syrup for a disabled child who takes 500mg daily for fever spikes, given that capsules are difficult to swallow, a prepared syrup causes gagging, and mixing the capsule contents with grenadine causes an immediate black discoloration, leading to concerns about potential oxidation, safety, and remaining efficacy?
Does the preparation of a minoxidil 5% solution with cetomacrogol 1000 and isopropanol still result in crystallization, and is the use of isopropanol instead of ethanol a possible cause for this?
What formula would you suggest for a stable nasal ointment or cream containing 5% minoxidil without corticosteroids, suitable for a general practitioner to prescribe?
How can Crestor 10 mg tablets be processed into a syrup for a 6-year-old child who cannot swallow tablets, will this suspension remain stable, what is its shelf life, and can the tablets be crushed and mixed with Fagron SyrSpend SF Cherry or should a suspension be prepared using tragacanth?
What is a suitable composition for an anesthetic ointment for permanent eyelid makeup in a patient with a lidocaine allergy, could benzocaine be used as an ester-based alternative after a prior skin patch test, and would a base of vaseline with a small amount of liquid paraffin be appropriate?
What are the stability problems of a solution containing 3 grams of Phenobarbital sodium and purified water up to 300 cc?
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